Depletion of platelets enhances therapeutic antitumor effects generated by therapeutic DNA vaccine
نویسندگان
چکیده
منابع مشابه
Depletion of platelets enhances therapeutic antitumor effects generated by therapeutic DNA vaccine
It has been well established that platelets are associated with tumor progression and metastasis as they can support angiogenesis and prevent hemorrhage. As such, platelets may be an ideal target for enhancing anticancer immunotherapies. Thus, we hypothesized that inducing thrombocytopenia would increase the leakiness of tumor vasculature thereby facilitating the effective delivery of antigen-s...
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ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2013
ISSN: 2051-1426
DOI: 10.1186/2051-1426-1-s1-p222